Survival of people living with HIV and AIDS monitored in the 17 antiretroviral treatment sites in Mali

Abstract

Introduction: In Mali, despite numerous prevention campaigns and the effectiveness of anti-retroviral therapy, cases of HIV-related deaths affect the productive layers much more. To better elucidate this observation, we studied the survival of People Living with HIV followed for 5 years in Mali. Material and methods: This was a cohort study, including 39,619 people living with HIV followed for 5 years at the 17 ESOPE sites in Mali. The data collected relate to those for the years 1999 to 2014, they were analyzed by the STATA software version 12. Results: Approximately 13% of the patients had died in the 5th year. The crude death rate was 10.22 person-years. On univariate analysis, women had a significantly lower risk of death (33%) than men (HR = 0.67, 95% CI = [0.62-0.72]). The risk-to-death ratio of patients receiving antiretroviral therapy was lower (43%) than those uninitiated to ARVs (HR = 0.57, 95% CI = [0.53-0.62]). Both in univariate and multivariate analysis, the risk of death of patients seen in WHO clinical stages 3 and 4 at baseline was significantly higher compared to those seen in stage 1. Conclusion: Our results showed that the survival proportion was 87%. WHO clinical stage, gender, antiretroviral therapy were risk factors associated with patient deaths.
Keywords: Survival, People living with HIV, 1999 to 2014.