Compliance related factors of Antiretroviral therapy (ART) at Care unit and accompaniments and Consulting (USAC) Koulikoro.

Abstract

Objective: The objective was to test a simple method adapted to the context of resources, limited area to measure adherence, and identify the reasons for non- compliance encountered in the monitoring of antiretroviral therapy (ART) in rural decentralized Mali. Method: This cross-sectional study in HIV patients followed in the outpatient USAC Koulikoro. Adherence to ART was measured by interviewing patients on regular renewal of the order. Patients were considered adherent if they reported never having failed one or more drug intake and never interrupted treatment. Results: The study focused on 250 patients. The age group 30 to 34 years was most represented in the series with 17.6%. The majority of patients were female is 75.1%. The majority of patients resided in the urban commune of Koulikoro is 74.4%. Figure 2 NRTIs NNRTI was the one prescribed in our patients is 91.6%. All patients were on ARV treatment, with 78% under Triomune (Lamivudine + Stavudine + Nevirapine in combination fixed). Patients who have a waiver (or refusal) to take the medication were 27.4% majority. Compliance was 75.2% of the overall index of compliance gives 188 patients (75.2%) and observant and 62 patients (24.8%) as non-compliant. Adherence in this study is relatively good (75.2% of patients). This study shows that the extent of compliance and feasible using the interview patients decentralized environment. The causes of inobservances were dominated by the refusal (27.4%) forgetfulness (24.2%) travel (16.1%), adverse effects of antiretroviral-type allergy (12.9%). Conclusion: In routine clinical practice, its use will assess patient compliance and improve decentralized environment in Mali.