Viral hepatitis B and C in blood donors of the national blood transfusion center Bamako, Mali

Abstract

The management of many pathological is not conceivable without the possibility of blood transfusion, but this therapy is not devoid of particular viral risks.In Mali, it is widely used, but in a difficult context, marked by a lack of resources, it is in this context that we undertook this study whose purpose was to determine the prevalence of HBV and HCV infectious markers in blood donors of Bamako.The prospective cross-sectional study was conducted between january and december 2017. A total of 48,508 blood donations were tested for HBsAg and anti-HCV antibodies. The enzyme immunoassay technique ELISA has been used with fourth-generation reagents. The frequency of HBs antigen carriage was 10.72% and seroprevalence of HCV was 1.53%. Replacement blood donations accounted for 73.69% of all blood collected with the highest prevalence of serological markers (HBV= 12.38%; HCV= 1.75%). This situation is comparable to many studies in Mali and sub-Saharan Africa. It is therefore necessary to intensify promotional activities in favor of voluntary donations, with a view to gradually abandoning the replacement donation. This is attested for Mali and is probably valid for most countries in sub-Saharan Africa.