Assessment of the management of patients with pharmaco-sensitive pulmonary tuberculosis at the Reference Health Center, Municipality V of Bamako, 2015-2018

Abstract

Introduction: In 2018, 6,605 cases of tuberculosis were notified in Mali. Bamako notified 2,102 cases (32%). Despite the efforts made, it constitutes a major public health problem. Objective: The objective was to evaluate the treatment of pulmonary tuberculosis in Commune V of Bamako from 2015 to 2018. Material and methods: We conducted a cross-sectional study from September to October 2019 on pulmonary tuberculosis cases series recorded at the Reference Health Center of Commune V in Bamako. In bivariate analysis, Odd Ratios were estimated and tested using the chi-square test at the 5% significance level. Results: A total of 1121 cases were included. The average age was 37 years ± 17 years for men and 35 years ± 15 years for women. New cases were represented with a proportion of 88.25%, 92.09%, 82.86% and 86.50% in 2015, 2016, 2017 and 2018 respectively. The relapse cases were 4.88% in 2017 and 6.34% in 2015. Co-infection with HIV ranged from 12.38% to 15.11%. Sputum analysis was the most common test performed between 76.36% and 91%. The 5^th month analysis showed a significant improvement for both 2015 and 2016 (p <0.0005) compared to the 2nd month. The proportion of cured patients was 53.97%, 46.40%, 57.86% and 56.90% for the four years respectively. Conclusion: Encouraging results have been obtained despite standing below the target cure rates