Improvement of the Circumstances of dermatological detection for HIV infection in Senegal: study from 2011 to 2020

Abstract

Objectives: draw up a new screening of dermatoses allowing the discovery of the infection and the immunological status of people living with HIV (PLWH) between 2011 and 2020.

Materials and methods: We made a cross-sectional study with retrospective multicenter recruitment over a period of 10 years. Patient’s files were collected in the two main references teaching hospital services in dermatology and sexually transmitted diseases (STD) in Senegal.  Were Included any patient record with HIV positive result. Data were analyzed on SPSS version 2.0 software. Results: We have collected 431 cases. The sex ratio was 0.52 and the mean age was 42.8 years. HIV1 represented 93.5% of cases. WHO stage 2 was noted in 196 cases (45.5%) followed by stage 3 in 119 cases (27.7%), stage 1 and 4 in respectively 59 cases (13.7%) and 57 cases (13.2%.The most dermatological DC's were in order of frequency: Herpes zoster (52%), prurigo (27.3%), oral candidiasis  (15%) and kaposi sarcoma (6.2%). The average baseline CD4 count was 271 cells / mm3. Oral candidiasis and prurigo were significantly linked with CD4 lower than 200 cells / mm3 (p = 0.0003 and p <0.0001 respectively) unlike viral dermatoses which are strongly correlated with CD4 uper than 200 cells / mm3.Conclusion: HIV infection is discovered increasingly early in Senegal. Infectious dermatoses are the main circumstances of discovery dominated by Herpes zoster