Profile of early-onset neonatal bacterial infections at Mother and Child Health Center of Maradi, Niger

Abstract

Objective: This study aimed to determine clinical and bacteriological profile of early-onset bacterial infections in Maradi.

Design: This was a descriptive prospective study from July to September 2018 at Maradi. Were included, all newborns aged zero to three days having criteria of neonatal infection (ANAES, 2002). Bacteriological examinations were done immediately after birth, using peripheral samples (external auditory meatus and meconium). Data analysis was done using Epi info 7.2.1 software.

Results: One hundred and fifty newborns were studied. The common anamnestic infectious criteria was premature rupture of membranes (65.33%). Most symptoms were respiratory signs (23%). CRP was greater than 20 mg / l in 44.44% of cases. Sixty-eight (45.33%) samples were positive. The main germs on the external auditory meatus were Staphylococcus aureus, Streptococcus agalactiae and Escherichia coli k1 were the most found germs with respectively 27 cases, 15 cases and 7 cases. The same germs were also reported in meconium with 11 cases, 6 cases and 5 cases respectively. Strains of staphylococci have good sensitivity to vancomycin (88.9%).

Conclusion: Because of their frequency, early-onset neonatal bacterial infections remain a public health problem in our countries. The bacterial ecology was dominated by Staphylococcus, most often indicative of nosocomial infection.