Central venous catheter-related infections in Bamako university hospitals

Abstract

Introduction: The aim of this study was to study infections linked to central catheters in university hospitals in Bamako

Patients and methods: This was a descriptive study with prospective collection over a period of two months. Inclusion concerned patients with a length of stay of more than 24 hours with the appearance of suspicious signs of infections linked to a central venous catheter. In the laboratory, the technique used was the simplified quantitative culture of Brun Buisson which defines the infection at more than 103 CFU / ml counted on the agar. Data entry and analysis was performed using SPSS 20.0 software.

Results: During the study period 27 patients met our inclusion criteria out of a total of 151 patients who received a central line during their stay. The mean age was 37.03 ± 15.43 years. Signs suggestive of catheter-related infection were fever (27 patients), pus at the insertion sites (5 patients) and redness of the skin in 3. The insertion site was femoral (22 patients), jugular (4 patients) and under keyboard in 1 patient. The mean length of stay for KTC was 8.96 ± 4.45 days with duration greater than 14 days in 37% of patients. The microorganisms found were fermentative BGN, non-fermentative BGN and Cocci gram positive with 9.8 and 3 cases respectively. The fermentative BGNs were Enterobacter cloacae (4 patients), Klebsiella pneumoniae (3 patients) and Escherichia coli in one patient. Two cases of bacteremia were found. Despite high resistance the majority of microorganisms retained susceptibility to amikacin.

Conclusion: This study confirms a high incidence of central line infections with high morbidity and mortality.