Renal affects in persons living with human immunodeficiency virus hospitalized in the internal medicine department of the university hospital center of “Point G”, Bamako (Mali).

Abstract

Introduction: Renal damage is common in human immunodeficiency virus (HIV) infection. Objective: To study the epidemiological, clinical and paraclinical aspects of kidney damage in people living with HIV (PLHIV). Materials and methods: We conducted a retrospective study (from January 1, 2013 to December 31, 2017) and a prospective study (from January 1, 2018 to December 31, 2018) of 5 years of data on the files of PLWHIV hospitalized in internal medicine at the university hospital (CHU) of Point G and presenting with kidney damage. Results: Among 336 PLWHIV, 30 had renal involvement, i.e. a prevalence of 9%. The mean age was 36.83 ± 12.93 years. The sample consisted of 16 women and 14 men with a sex ratio of 0.9. The urinary signs were dysuria in 04 cases (13.3%), oliguria in 04 cases (13.3%), and anuria in 2 cases (6.7%). The main renal disorders were: chronic renal failure (100%), proteinuria (80%), isolated leukocyturia 03 cases, and urinary infection 04 cases (36.37%). Ultrasound (n=23) showed diminished kidneys (05 cases), poorly differentiated (14 cases), dilated (04 cases). The case fatality rate was 53.33%. Conclusion: This study shows that the frequency of renal damage in persons living with human immunodeficiency virus is high. Close monitoring of renal function in these patients is therefore essential.