Antibiotics susceptibility profile of Escherichia coli isolates from suppurations at the referral hospital of Bobo-Dioulasso, Burkina Faso

Abstract

Background: This study aimed to investigate on the antibiotics susceptibility profile of Escherichia coli isolates from suppurations at the Sourô Sanou University Hospital Centre.

Methodology: A descriptive cross-sectional study was conducted from January 1^st to December 31^th, 2020 at the Sourô SANOU University Hospital Centre, the referral hospital of Bobo-Dioulasso. Pus samples of in-patients were collected and subjected to cytological and bacteriological tests.

Results: Of 552 specimens processed in this study, 324 were culture- positive. The prevalence of E. coli infections was 17.64% [95% CI: 14.66 – 21.06] in the suppurations. Male sex was predominant with a sex ratio of 1.5. The age group [20-24 years] was the most affected and accounted for 10.30%. E. coli infections were more frequent in the surgery office (50.52%). There was a very good susceptibility of E. coli strains to imipenem (96%), amikacin (93%) and gentamicin (52%). But some strains were resistant to Cefotaxim (23%), ciprofloxacin (27%), amoxicillin (7%) and amoxicillin + clavulanic acid (3%). Extended Spectrum beta-lactamase (ESBL) was produced by 34% (33/97) E. coli strains.

 Conclusion: This study pointed out that imipenem, amikacin and gentamicin were active in suppurative infections caused by E. coli strains. The prescription of these antibiotics must be rational in the surgery office